Innovation Matching Grants Program

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Objective

Empire State Development’s Division of Science, Technology, and Innovation (“NYSTAR”), Innovation Matching Grants (IMG) Program aims to grow small businesses and support the development of new technologies in New York State by providing matching funds for federal Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) grants.

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Overview

The New York State Innovation Matching Grants Program will match:

  • The award for Phase I applicants, not to exceed $100,000
  • The award for Phase II applicants, not to exceed $200,000
  • and provide technical assistance resources for Phase II and Phase III awards.

In no event, shall the funding provided from the IMG Program exceed 50% of the federal award. 

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Eligibility

Eligible applicants must:

  1. Be a small business as defined by New York State Economic Development Law Section 131. This includes businesses that are:
    • resident in New York State;
    • independently owned and operated, not dominant in their field; and
    • employing 100 or less persons.
       
  2. Actively in the process of applying for a Phase I or Phase II SBIR or STTR award from a participating federal agency or have received an SBIR/STTR award since the closing date of previous announced round or 12 months, whichever is less.
     
  3. Currently operate their business in New York.
    • Note: IMG Program grant recipients must remain headquartered and operate or manufacture in New York State for at least two years following the successful commercialization of the IMG Program grant recipient’s product or products. Any IMG Program grant recipient that does not do so shall return all IMG Program grant funds to NYSTAR. If the IMG Program grant recipient ceases operations before five years, such IMG Program grant recipient shall be eligible for a waiver of this claw back provision, as determined by NYSTAR, in consultation with Empire State Development’s division for small business.

IMG Program grant funds shall be used to expedite commercialization and generally used to cover expenses not allowed under SBIR or STTR, including but not limited to business planning, commercialization, patents, and marketing studies in sales efforts.

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How to Apply

Please review before applying:

Program Guidelines - updated 9/11/25

FAQ 

Eligibility Template

Application Template

*A single business may only submit one application per round. A business may not apply for a Phase I or Phase II award for which they have already received any IMG Program matching grant. *

Rounds for the Innovation Matching Grants Program will open at 9:00am on the 2nd Wednesday in October & April. Rounds will remain open for 1 week, closing the following Tuesday at 5:00pm. Applications are digital, and a link will be provided to the application when the round opens.

Round 4 is now closed. 

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Portfolio

The Innovation Matching Grants Program portfolio includes all who received an award or commitment letter and were listed in our press release at the time of the round. Awards are conditioned on the successful SBIR/STTR federal award and negotiation and execution of a Grant Disbursement Agreement. 

Year Round Award/Commitment Letter SBIR/STTR Phase I/II Business Name Technology Focus Area Region
2024 2 Award Letter SBIR Phase I  Addinex Technologies, Inc. Additive / Manufacturing Technologies Other New York City
2024 1 Award Letter SBIR  Phase I Aincobio LLC Lifesciences / Biotechnology Central NY
2025 3 Commitment Letter SBIR Phase I Albacore Ocean Systems LLC Additive / Manufacturing Technologies Robotics / Co-bots Artificial Intelligence Unmanned Aerial Systems (UAS) / Drones Energy Systems Sensors Communications New York City
2024 1 Award Letter SBIR Phase II Alpha-En Corporation Energy Storage / Battery Technology Renewables / Clean / Green Technologies Mid-Hudson
2025 3 Award Letter SBIR Phase II ANDRO Computational Solutions, LLC Artificial Intelligence Communications Mohawk Valley
2024 2 Commitment Letter SBIR  Phase I Anew Material (previously Keratin Nails LLC) Additive / Manufacturing Technologies Renewables / Clean / Green Technologies Materials New York City
2025 3 Award Letter SBIR Phase I Anova Biomedical, Inc. Lifesciences / Biotechnology Southern Tier
2025 3 Award Letter STTR Phase I ARMA BIO INC Lifesciences / Biotechnology New York City
2025 3 Commitment Letter SBIR Phase I Astrabeam LLC Semiconductors / Nanotechnology / Nanoelectronics Space Technology Sensors New York City
2024 2 Commitment Letter STTR Phase II Atrevida Science Inc. Artificial Intelligence Renewables / Clean / Green Technologies Western NY
2025 3 Award Letter STTR Phase I BeamFeed LLC Unmanned Aerial Systems (UAS) / Drones Advanced Photovoltaics Semiconductors / Nanotechnology / Nanoelectronics New York City
2025 3 Award Letter SBIR Phase I BiRed Imaging, Inc. Lifesciences / Biotechnology Finger Lakes
2025 3 Award Letter SBIR Phase I Brooklyn InnoSeq Inc Lifesciences / Biotechnology New York City
2025 3 Award Letter SBIR Phase I Calyx Systems Lifesciences / Biotechnology Semiconductors / Nanotechnology / Nanoelectronics New York City
2024 1 Award Letter STTR Phase I Carbon To Stone, Inc. Renewables / Clean / Green Technologies Materials Finger Lakes
2025 3 Commitment Letter STTR Phase I Care4QoL LLC Artificial Intelligence Wearable Devices Sensors Capital Region
2024 2 Award Letter SBIR Phase I Chimerna Therapeutics Lifesciences / Biotechnology Cell or Gene Therapy Vaccines Additive / Manufacturing Technologies New York City
2024 2 Commitment Letter SBIR Phase I Circadian OS Lifesciences / Biotechnology New York City
2024 1 Award Letter SBIR Phase I DataCicada LLC Artificial Intelligence Lifesciences / Biotechnology Sensors Renewables / Clean / Green Technologies Robotics / Co-bots Finger Lakes
2025 3 Commitment Letter SBIR Phase I ecoLong LLC Sensors Artificial Intelligence Food or Agriculture Technology Energy Systems Smart Grid Capital Region
2025 3 Award Letter SBIR Phase I Ergami Endoscopy, Inc. Lifesciences / Biotechnology Robotics / Co-bots New York City
2024 2 Award Letter SBIR Phase I ESM Global Productions, LLC Artificial Intelligence New York City
2024 1 Award Letter SBIR Phase II Graphenix Development, Inc. Energy Storage / Battery Technology Renewables / Clean / Green Technologies Materials Western NY
2025 3 Commitment Letter SBIR Phase I Hebbian Bio Inc Lifesciences / Biotechnology New York City
2024 1 Award Letter SBIR Phase II IAMBIC INC. Additive / Manufacturing Technologies Artificial Intelligence Other New York City
2024 1 Award Letter SBIR Phase II IBEX Materials Inc. Energy Storage / Battery Technology Materials Western NY
2025 3 Award Letter SBIR Phase II iHealthScreen Inc Additive / Manufacturing Technologies Artificial Intelligence Lifesciences / Biotechnology New York City
2024 2 Commitment Letter SBIR Phase I IMMUNOTOLERX THERAPEUTICS LLC Lifesciences / Biotechnology Western NY
2024 2 Award Letter SBIR Phase I KLAW Industries Artificial Intelligence Renewables / Clean / Green Technologies Robotics / Co-bots Southern Tier
2025 3 Commitment Letter SBIR Phase II KLAW Industries Renewables / Clean / Green Technologies Materials Southern Tier
2024 2 Award Letter SBIR  Phase II Labby Food or Agriculture Technology Sensors Lifesciences / Biotechnology Artificial Intelligence Finger Lakes
2024 2 Award Letter STTR Phase I LiBAMA Power Energy Storage / Battery Technology Southern Tier
2024 2 Award Letter SBIR Phase II LighTopTech Corp. Artificial Intelligence Lifesciences / Biotechnology Other Finger Lakes
2024 2 Award Letter SBIR Phase I Lucerna, Inc. Lifesciences / Biotechnology New York City
2024 2 Commitment Letter SBIR Phase I Manhattan BioSolutions, Inc. Lifesciences / Biotechnology New York City
2024 2 Award Letter SBIR Phase II Mission Power Energy Systems Renewables / Clean / Green Technologies North Country
2025 3 Commitment Letter SBIR  Phase I Mission Power Corp. Renewables / Clean / Green Technologies North Country
2025 3 Award Letter SBIR Phase II Natrion Inc. Energy Storage / Battery Technology Southern Tier
2024 1 Award Letter STTR Phase I Nearabl Inc. Artificial Intelligence Augmented Realty/Virtual Reality New York City
2025 3 Commitment Letter STTR  Phase II Nearabl Inc. Artificial Intelligence Augmented Realty/Virtual Reality New York City
2024 2 Award Letter STTR Phase I Nephrogen Inc. Cell or Gene Therapy Lifesciences / Biotechnology New York City
2025 3 Award Letter STTR Phase I Neuralenz Sensors Lifesciences / Biotechnology Other Semiconductors / Nanotechnology / Nanoelectronics New York City
2025 3 Award Letter STTR  Phase I NoMIS Power Corporation Energy Storage / Battery Technology Smart Grid Semiconductors / Nanotechnology / Nanoelectronics Energy Systems Renewables / Clean / Green Technologies Capital Region
2024 2 Award Letter STTR Phase II Pharmacoustics Technologies, LLC Lifesciences / Biotechnology Sensors Additive / Manufacturing Technologies North Country
2024 1 Award Letter SBIR Phase I Photonect Interconnect Solutions Inc. Semiconductors / Nanotechnology / Nanoelectronics Quantum Finger Lakes
2025 3 Commitment Letter SBIR Phase I PlasmaChem Solutions Inc. Energy Systems Hydrogen Fuel Cells & Hydrogen Distribution Renewables / Clean / Green Technologies Western NY
2025 3 Commitment Letter SBIR Phase II QAS.AI Inc Artificial Intelligence Lifesciences / Biotechnology Western NY
2024 2 Award Letter STTR Phase I Retrn Bioworks Inc. Renewables / Clean / Green Technologies Food or Agriculture Technology Materials Finger Lakes
2025 3 Commitment Letter SBIR Phase I Sunrise Technology Inc. Artificial Intelligence Smart Grid Long Island
2024 2 Award Letter SBIR Phase II SunThru LLC Additive / Manufacturing Technologies Materials Capital Region
2024 2 Award Letter SBIR Phase II SUPERClean Glass Inc. Renewables / Clean / Green Technologies Advanced Photovoltaics Smart Grid Additive / Manufacturing Technologies Energy Systems Long Island
2024 1 Award Letter STTR Phase I sxRNA Technologies, Inc. Lifesciences / Biotechnology Cell or Gene Therapy Sensors Additive / Manufacturing Technologies Capital Region
2025 3 Commitment Letter SBIR Phase I SynchroPET Lifesciences / Biotechnology Long Island
2024 1 Award Letter SBIR  Phase II Tezcat Biosciences, Inc. Lifesciences / Biotechnology New York City
2024 2 Award Letter STTR Phase I UbiquiTx Inc. Lifesciences / Biotechnology New York City
2025 3 Award Letter STTR Phase II VoiceLove, LLC Other New York City
2024 2 Award Letter SBIR Phase I Vyir Inc Sensors Renewables / Clean / Green Technologies Unmanned Aerial Systems (UAS) / Drones Semiconductors / Nanotechnology / Nanoelectronics New York City
2024 1 Commitment Letter SBIR Phase I Xallent Inc. Semiconductors / Nanotechnology / Nanoelectronics Capital Region
2024 2 Award Letter SBIR Phase I Xylyx Bio, Inc. Lifesciences / Biotechnology New York City
2024 1 Commitment Letter SBIR Phase I Zetagen Therapeutics Inc Lifesciences / Biotechnology Central NY